The most abundant endocannabinoid found in the body, 2-Arachidonoylglycerol (2-AG) is a member of a group of molecules that play a complex and important role in various bodily processes including immunity and inflammation. Like anandamide, 2-AG is thought to help regulate appetite, immune system function, and pain management by interacting with the body’s endocannabinoid system receptors.
A major endocannabinoid naturally found in the body. Like 2-AG, anandamide is part of the body’s endocannabinoid system and alters functions like cognition, learning, memory, mood, other higher intellectual functions, and certain motor functions. THC is thought to produce psychoactive effects and alter these same functions in the body because it mimics the way anandamide interacts with the endocannabinoid system.
This term refers to the degree and rate at which a drug is absorbed by the body’s circulatory system. It’s an important measurement tool because it determines the correct dosage for non-intravenously administered drugs. For drugs, supplements, and herbs administered non-intravenously (such as through consumption, inhalation, or topical application) bioavailability designates the fraction of the ingested dose that eventually gets absorbed.
Products labeled “broad spectrum” fall somewhere between full-spectrum and isolate formulations. Because they contain terpenes and other beneficial cannabinoids, broad-spectrum products offer some of the benefits of the entourage effect — without any THC. For those who can’t have or don’t want to have any traces of THC in their system, broad-spectrum products can be a better choice than isolates. But they’re not as effective as full-spectrum products.
Also known as CBD, cannabidiol is one of the naturally occurring cannabinoids found in cannabis plants. It’s the second most prevalent active ingredient in cannabis, accounting for up to 40% of the plant’s extract. CBD does not produce psychoactive effects. Cannabidiol interacts with the endocannabinoid system (ECS), part of the nervous system that’s thought to play a regulatory role in all kinds of bodily functions, including mood, sleep, and appetite. According to a 2017 report from the World Health Organization, there is evidence that CBD is an effective treatment for epilepsy.
Not to be confused with cannabidiol (cannabidiol is a cannabinoid, but not all cannabinoids are cannabidiol), a cannabinoid is one of the diverse chemical compounds that acts on the endocannabinoid system receptors found throughout the body. These molecules include the endocannabinoids produced naturally in the body and phytocannabinoids from cannabis. The two most notable cannabinoids are THC and CBD.
Cannabis, also known as marijuana among other names, is a psychoactive drug from the Cannabis plant used for medical or recreational purposes. The primary psychoactive component of cannabis is tetrahydrocannabinol, one of the 483 known compounds in the plant, including at least 65 other cannabinoids.
Indigenous to eastern Asia, this flowering herbaceous plant has been farmed throughout recorded human history. It is farmed for marijuana as well as the industrial hemp used in CBD products. In addition, hemp fiber, hemp seed oil, and food products are also derived and harvested from different parts of the plant.
A delivery method for CBD oils and extracts that’s easy to swallow (literally). Capsule products resemble the gel pills you’re used to seeing at your local pharmacy.
Cannabidiol (CBD) is a non psycho-active compound of cannabis and is one of the 150+ naturally occurring phytocannabinoids found in certain strains of hemp and in all cannabis plant strains.
These products are 99% CBD. To manufacture an isolate, everything contained in the plant matter is removed — including any traces of THC and other beneficial cannabinoids — until only a powder or crystalline form of CBD is left. This means that isolate users will not benefit from the entourage effect.
Cannabigerol is one of more than 120 identified cannabinoid compounds found in the plant genus Cannabis. Cannabigerol is the non-acidic form of cannabigerolic acid, the parent molecule from which other cannabinoids are synthesized. Cannabigerol is a minor constituent of cannabis. https://en.wikipedia.org/wiki/Cannabigerol
Unlike CBD, which has a relatively low affinity for cannabinoid receptors and acts mostly through indirect interactions with the endocannabinoid system, CBG is thought to elicit its therapeutic effects directly though interaction with the CB1 and CB2 cannabinoid receptors in the brain.
The psychoactive cannabinoid THC also produces its psychoactive effects though interactions with these receptors; CBG has been observed to work as a buffer to THC’s psychoactivity and can even alleviate the feelings of paranoia that sometimes come with consumption of high levels of THC.
Research is relatively sparse regarding the therapeutic benefits of CBG, when compared to the apparent wealth of information available on THC and CBD within the cannabis science community. But there are early studies linking the compound to a whole host of potential therapeutic uses, such as:
- Treating glaucoma, though its vasodilator and neuroprotective effects.
- Decreasing inflammation, as seen in animal models of inflammatory bowel disease.
- Combatting Huntingdon's disease, again through its neuroprotective effects.
- Inhibiting tumor growth, in animal models of colorectal cancer.
- Killing drug-resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA).
Certificate of analysis (COA)
A document from an accredited laboratory certifying the amount of cannabinoids in a given product. This proof of analysis exists to benefit the consumer as much as the producer: It guarantees quality assurance for both parties. Reviewing the COA is a pro consumer move that helps you avoid mislabeled, low-quality, or fake products. A reputable company will always provide one.
The carbon-dioxide extraction process uses changes in temperature and pressure to create phase changes in carbon dioxide, gently drawing out the plant’s beneficial components. The result is clean, safe oil with a long shelf life.
How a drug enters the body in order to produce the desired therapeutic effects. The delivery method of a given drug can affect how quickly it starts working and how much of each dose gets absorbed by the body (bioavailability). CBD delivery methods include ingestible capsules, gummies, and tinctures, as well as topical lotions, salves and lip balms.
Known by the abbreviation THC, this is a primary cannabinoid found in cannabis and the one responsible for its psychoactive effects. It works on endocannabinoid receptors in the brain to release dopamine. Some dislike the “high” feeling or other side effects of this chemical and prefer hemp-based products that contain very little to no THC.
Dietary supplements are products intended to supplement the diet. They are not medicines and are not intended to treat, diagnose, mitigate, prevent, or cure diseases.
Any food containing some form of cannabis. Pot brownies are the most classic example, but nowadays, cannabis-infused edibles come in many other forms: candy, coffee, baked goods, martinis, even infused butter and cooking oil.
Also known as the ECS, the main function of this mammalian system is to maintain bodily homeostasis, or keeping the body balanced even when the environment changes. Scientists believe that cannabis is effective, in part, because the phytocannabinoids it contains mimic our endocannabinoids. Endocannabinoid receptors are found throughout the entire body, and the system plays a part in many of the body’s processes, including appetite, stress, sleep, pain, memory, and immune function.
This phenomenon is all about teamwork: It’s the result of the many components in the cannabis plant interacting together with the human body to produce a stronger effect than any one component on its own. Full-spectrum CBD products combine CBD with other naturally occurring terpenes and cannabinoids (including THC) to be more effective than their isolate counterparts.
Extraction using cold, high-grade alcohol gently pulls all the active compounds from the cannabis plant’s cellulose material, resulting in pure, full-spectrum hemp oil. Oils extracted using this method are further refined via chromatography to remove all remaining traces of ethanol.
The process of deriving CBD oil from hemp. There are several methods of extracting CBD from cannabis plants, including CO2 and cold ethanol extraction.
United States Congress voted at the end of December 2018 to pass the Agriculture Improvement Act of 2018, more commonly referred to as the Farm Bill. This legislation made CBD products legal to purchase in all 50 states. Under the Farm Bill, industrial hemp (where CBD products are derived from) must contain less than .3 % THC. The power over industrial hemp regulation is shared by the state and federal governments. The Farm Bill also gave the FDA the authority to regulate cannabis products.
The U.S. Food and Drug Administration (FDA) is a regulatory government agency with the power to regulate cannabis and cannabis-derived products since the passing of the 2018 Farm Bill. So far, the FDA has officially approved the CBD product Epidiolex as a treatment for epilepsy. The government’s relationship with the cannabis industry is constantly evolving; learn more about about how the FDA is handling cannabis and CBD products on the FDA’s website.
CBD that’s full of all the terpenes, cannabinoids, flavonoids, and fatty acids found in hemp, all of which have therapeutic value of their own and help create what’s known as the entourage effect. Basically, full-spectrum CBD can give you every potential benefit the plant has to offer.
Gluten Free simply means no chemical additives, flavorings, and/or preservatives are added to the product.
Ss a strain of the Cannabis sativa plant species that is grown specifically for the industrial uses of its derived products. Hemp used in CBD products must contain less than .3% THC.
Hemp Seed Oil
Derived from industrial hemp, hemp seed oil is created by pressing the plant’s seeds. It has no therapeutic benefits but is often used as a dietary supplement and a low-saturated-fat cooking oil.
Hemp grown specifically for the industrial uses of its products, including textiles, clothing, biodegradable plastic, food, biofuel, and medicine (including CBD). Hemp and its products are legal in the U.S. under the Farm Bill as long as they contain less than .3% THC.
A general term that refers to female Cannabis sativa plants that produce flowers containing phytocannabinoids that are used for their medicinal and psychoactive properties.
A technique that involves consuming small servings of CBD supplements throughout the day. Microdosing can be beneficial because it allows the user to maintain stable CBD levels in your system around the clock. This consistency can be important for those who use CBD for its balancing properties.
Also known as dietary supplements, these are food-derived products that offer extra health benefits in addition to their existing nutritional value. These products that contains nutrients derived from food products and are often concentrated in liquid, capsule, powder, or pill form. Dietary supplements are regulated by the FDA.
Foods and products derived from farming methods that promote ecological balance and restrict the use of pesticides, fertilizers, and synthetics. These growing practices promote the health of both the environment and the consumer. Organic products particularly appeal to those who support sustainable farming and care about the safety and quality of what goes into their bodies.
The chemical compounds in cannabis plants that mimic the endocannabinoids naturally produced by the body. CBD and THC are examples of phytocannabinoids, but there are at least 113 different phytocannabinoids in the cannabis plant, each producing unique effects in the body.
A measure of drug activity expressed in terms of the amount required to produce an effect of given intensity in the body. A high-potency drug evokes a larger response even at a low dose, while a low-potency drug evokes a small response at low concentrations and requires higher doses for a similar effect.
A property that changes brain function by interacting with the central nervous system and results in altered perception, mood, consciousness, cognition, or behavior. THC is the primary psychoactive component in cannabis plants.
An ointment made from the cannabis plant to be applied directly to the skin.
A cannabis plant bred for certain characteristics and use in medicinal, recreational, or industrial purposes. Industrial hemp, for example, is a strain bred to contain more CBD and less THC than other varieties, making it useful for medicinal products and legal under the Farm Bill.
From the Latin for “under the tongue,” a method for administering drugs by mouth. It involves placing a substance under the tongue, where it can be readily absorbed into the blood vessels and begin to circulate throughout the body.
Aromatic oils that lend flavors such as berry, mint, and pine to different cannabis strains. More than 100 different terpenes have been identified, and every cannabis strain has its own terpene profile. The effects of any given terpene may be amplified in the presence of other compounds (also known as the entourage effect).
Tetrahydrocannabinol (THC) is the chemical in cannabis that causes the high.
A delivery method, typically administered sublingually, that quickly absorbs and distributes throughout the body.
A delivery method where product is applied to the skin, typically as a salve or lotion, over the areas where they’re needed.
A business practice where a company owns its own supply chain. For example, owning the farms where hemp is grown, the barns where it’s stored, and the labs where it’s processed. This means that a vertically integrated company can ensure tighter quality control and maintain their core values and practices across all parts of the production process.